Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2011-03-15
2011-03-15
Desai, Anand U (Department: 1656)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S069100, C435S106000, C435S440000, C435S006120, C530S350000
Reexamination Certificate
active
07906636
ABSTRACT:
The present invention relates generally to fluorescent proteins and fluorescent protein variants, and more specifically to monomeric and dimeric forms of Anthozoan fluorescent proteins. In one aspect, the present invention provides variants of fluorescent proteins, where the variants have a reduced propensity to tetramerize, and form dimeric or monomeric structures. In a further aspect, the present invention provides variants of fluorescent proteins, the variants being characterized by more efficient maturation than corresponding fluorescent proteins from which they are derived. The invention also relates to methods of making and using such fluorescent proteins and fluorescent protein variants, including fluorescent protein monomers and dimers.
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Campbell Robert E.
Shaner Nathan C.
Tsien Roger Y.
Desai Anand U
Liu Samuel
Morgan & Lewis & Bockius, LLP
Parent Annette S.
The Regents of the University of California
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