Monohydrate and DMF solvates of a new carbacephem antibiotic

Details Monohydrate and DMF solvates of a new carbacephem antibiotic Monohydrate and DMF solvates of a new carbacephem antibiotic

1990-10-23

1992-02-25

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D46300

Patent

active

050915258

ABSTRACT:
The crystalline monohydrate, mono (N,N'-dimethylformamide) and bis(N,N'-dimethylformamide) solvates of 7.beta.-[2'-(R)-2'-(p-hydroxyphenyl-2'-amino-acetamido]-3-chloro-3-(1-carb adethiacephem)-4-carboxylic acid ("LY213735") are novel compounds with superior physical characteristics. Also described are pharmaceutical formulations of crystalline LY213735 monohydrate.

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Merck Index, 10th Edition (1983), pp. 267-8.
Merck Index, 10th Edition, Entry 1896.
Herman, Chem. Abs. 94, 90151t (1980).

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