Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1996-12-20
1999-07-13
Minnfield, Nita
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
4353201, 435 691, 4352523, 536 231, 536 235, C12N 1563, C12N 1500, C12N 1585, C07H 2104
Patent
active
059225408
ABSTRACT:
The invention provides isolated nucleic acid compounds encoding a novel MTG of Staphylococcus aureus. Also provided are vectors and transformed heterologous host cells for expressing the MTG and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the MTG.
REFERENCES:
Paik et al, 1997, J. Bacteriol, 179(12): 4061-65.
Borchardt et al 1993. Gene 137:253-258.
M. Di Berardino, et al., "The monofunctional glycosyltransferase of Escherichia coli is a member of a new class of peptidoglycan-synthesising enzymes" FEBS Letters, 392, pp. 184-188, (1996).
Hoskins Jo Ann
Jaskunas, Jr. Stanley R.
Peery Robert B.
Skatrud Paul L.
Eli Lilly and Company
Minnfield Nita
Stewart Mark J.
Webster Thomas D.
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