Monoesters of rosamicin for eliciting an antibacterial response

Details Monoesters of rosamicin for eliciting an antibacterial response Monoesters of rosamicin for eliciting an antibacterial response

1977-01-13

1978-02-21

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Combination of antigens from multiple bacterial species

424279, A61K 31665, A61K 31335

Patent

active

040753310

ABSTRACT:
Described herein are novel monoesters of rosamicin, also known as Antibiotic 67-694. Also described is a process for the preparation of such esters by the selective solvolysis of diester precursors. The monoesters are broad spectrum antibacterial agents but are generally more effective against gram-positive bacteria.

REFERENCES:
reimann et al., J.C.S. Chem. Comm., p. 1270 (1972).

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