Monoclonal IgA antibody specific for respiratory syncytial virus

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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43524027, 435 794, 435 7021, 4351722, 5303883, 5303911, 5303913, 436548, G01N 3353, C07K 1608, C12N 520

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055344119

ABSTRACT:
A new hybridoma cell line HNK20 which secretes a monoclonal IgA antibody to respiratory syncytial virus is disclosed. The antibody has diagnostic uses in respect of Respiratory Syncytial Virus.

REFERENCES:
patent: 4800078 (1989-01-01), Prince et al.
patent: 5223254 (1993-06-01), Paradiso et al.
Barbas III et al., Human Monoclonal Fab Fragments Derived from a Combinatorial Library Bind to Respiratory Syncytial Virus F Glycoprotein and Neutralize Infectivity, Proc. Natl. Acad. Sci. USA 89:10164-10168, 1992.
Fischer, Therapeutic Uses of Intravenous Gammaglobulin for Pediatric Infections, Pediatric Clinics of North America 35:517-533, 1988.
Groothuis and Simoes, Immunoprophylaxis and Immunotherapy: Role in the Prevention and Treatment of Respiratory Syncytial Virus, International J. Antimicrobial Agents 2:97-103, 1993.
Groothuis et al., Prophylactic Administration of Respiratory Syncytial Virus Immune Globulin to High-Risk Infants and Young Children, N. Engl. J. Med. 329:1524-30, 1993.
Kennedy et al., Production and Characterization of Bovine Monoclonal Antibodies to Respiratory Syncytial Virus, J. Gen. Virol. 69:3023-3032, 1988.
Taylor et al., Monoclonal Antibodies Protect Against Respiratory Syncytial Virus, The Lancet II:976, 1983.
Nandapalan et al., Mammary and Serum Antibody Levels to RS Virus in Mothers Exposed to Respiratory Syncytial Virus, Sixth International Congress of Virology Abstracts 260:P36-2, 1984.
Okamoto et al., Effect of Breast Feeding on the Development of Anti-Idiotype Antibody Response to F . . . Syncytial Virus In Infant Mice After Post-Partum Maternal Immunization, J. Immunology 142:2507-2512, 1989.
Piazza et al., Immunotherapy of Respiratory Syncytial Virus Infection in Cotton Rats (Sigmodon fulviventer) Using IgG in a Small_-Particle Aerosol, J. Infectious Diseases 166:1422-1444, 1992.
Prince et al., Effectiveness of Topically Administered Neutralizing Antibodies in Experimental Immunotherapy of Respiratory Syncytial Virus Infection in Cotton Rats, J. Virology 61:1851-1854, 1987.
Prince et al., Mechanisms of Immunity to Respiratory Syncytial Virus in Cotton Rats, Infection and Immunity 42:81-87, 1983.
Russell et al., Principles of Antibody Therapy, British Medical Journal 305:1424-1429, 1992.
Suffin et al., Immunoprophylaxis of Respiratory Syncytial Virus Infection in the Infant Ferret, J. Immunol. 123:10-14, 1979.
Taylor et al., Humanised Monoclonal Antibody to Respiratory Syncytial Virus, The Lancet 337:1411-1412, 1991.
Tempest et al., Reshaping a Human Monoclonal Antibody to Inhibit Human Respiratory Syncytial Virus Infection In Vivo, Bio/Technology 9:266-271, 1991.
Trudel et al., Protection of BALB/c Mice from Respiratory Syncytial Virus Infection by Immunization with a Synthetic Peptide Derived from the G Glycoprotein, Virology 185:749-757, 1991.
Walsh and Hruska, Monoclonal Antibodies to Respiratory Syncytial Virus Proteins: Identification of the Fusion Protein, J. Virology 47:171-177, 1983.
Beeler et al., "Neutralization Epitopes of the F Glycoprotein of Respiratory Syncytial Virus: Effect of Mutation upon Fusion Function", Journal of Virology 63:2941-2950, 1989.
Belshe et al., "Parenteral Adminstration of Live Respiratory Syncytial Virus Vaccine: Results of a Field Trial", The Journal of Infectious Diseases 145:311-319, 1982.
Brideau et al., "Protection of Cotton Rats against Human Respiratory Syncytial Virus by Vaccination with a Novel Chimeric FG Glycoprotein", J. Gen. Virol. 70:2637-2644, 1989.
Bruhn et al., "Respiratory Syncytial Virus in Early Infancy", Am J Dis Child 131:145-148, 1977.
Collins et al., "Evaluation in chimpanzees of vaccinia virus recombinants that express the surface glycoproteins of human respiratory syncytial virus", Vaccine 8:164-168, 1990.
Connors et al., "Respiratory Syncytial Virus (RSV) F, G, M2 (22K), and N Proteins Each Induce Resistance to RSV Challenge, but Resistance . . . N Proteins Is Relatively Short-Lived", J. Virology 65:1634-1637, 1991.
Connors et al., "Cotton rats previously immunized with a chimeric RSV FG glycoprotein develop enhanced pulmonary pathology when infected with RSV, . . . " Vaccine 10:475-484, 1992.
Elango et al, "Resistance to human respiratory syncytial virus (RSV) infection induced by immunization of cotton rats with a recombinant . . . " Proc. Natl. Acad. Sci. USA 83:1906-1910, 1986.
Fenner, "The Classification and Nomenclature of Viruses Summary of Results of Meetings of the International Committee on Taxonomy of Viruses in Madrid, Sep. 1975", Virology, 71:371-378, 1976.
Garcia-Barreno et al., "Marked Differences in the Antigenic Structure of Human Respiratory Syncytial Virus F and G Glycoproteins", Journal of Virology 63:925-932 Feb. 1989.
Glezen et al., "Risk of Primary Infection and Reinfection With Respiratory Syncytial Virus", 140:543-546, 1986.
Graman et al., "Epidemiology and Control of Nosocomial Viral Infections", Infectious Diseases Clinics of North America 3:815-841, 1989.
Groothuis et al., "Use of Intravenous Gamma Globulin To Passively Immunize High-Risk Children against . . . Virus: Safety and Pharmacokinetics", Antimicrobial Agents and Chemotherapy 35:1469-1473, 1991.
Hall et al., "Immunity to and Frequency of Reinfection with Respiratory Syncytial Virus", The Journal of Infectious Diseases 163:693-698, 1991.
Hall et al., "Modes of transmission of respiratory syncytial virus", The Journal of Pediatrics 99:100-103, 1981.
Hemming et al., "Intravenous immunoglobulin G in viral respiratory infections for newborns and infants", 5:S204-S206, 1986.
Huang et al., "The Genome of Respiratory Syncytial Virus is a Negative-Stranded RNA That Codes for at Least Seven mRNA Species", Journal of Virology, 43:150-157, 1982.
Johnson et al., "The G glycoprotein of human respiratory syncytial viruses of subgroups A and B: Extensive sequence divergence between antigenically . . . ", Proc. Natl. Acad. Sci. USA 84:5625-5629, 1987.
Kanesaki et al., "Effectiveness of Enteric Immunization in the Development of Secretory Immunoglobulin A Response and the Outcome of Infection . . . ", Journal of Virology 65:657-663, 1991.
Kapikian et al., "An Epidemiologic Study of Altered Clinical Reactivity to Respiratory Syncytial (RS) Virus Infection in Children Previously . . . ", American Journal of Epidemiology 89:405-421, 1969.
Kaul et al., "Secretory Antibody Response to Respiratory Syncytial Virus Infection", Am. J. Dis. Child, 135:1013-1016, 1981.
Kauppi et al., "Anti-Capsular Polysaccharide Antibodies Reduce Nasopharyngeal Colonization by Haemophilus influenzae Type b in Infant Rats", The Journal of Infectious Diseases 167:365-371, 1993.
Kim et al., "Safety and Antigenicity of Temperature Senstitive (TS) Mutant Respiratory Syncytial Virus (RSV) in Infants and Children", Pediatrics 52:56/72-63/79, 1973.
King et al., "Recombinant Vaccinia Viruses Carrying the N Gene of Human Respiratory Syncytial Virus: Studies of Gene Expression in Cell . . . ", Journal of Virology 61:2885-2890, 1987.
Kohler et al., "Fusion between immunoglobulin-secreting and nonsecreting myeloma cell lines", Eur. J. Immunol. 6:292-295, 1976.
Lopez et al., "Location of a Highly Conserved Neutralizing Epitope in the F Glycoprotein of Human Respiratory Syncytial Virus", Journal of Virology 64:927-930, 1990.
McIntosh et al., "Respiratory Syncytial Virus", Virology, Second Edition, Chapter 38, pp. 1045-1072, 1990.
McIntosh et al., "The Immunologic Response to Infection with Respiratory Syncytial Virus in Infants", The Journal of Infectious Diseases 138:24-32, 1978.
McIntosh et al., "Attenuated Respiratory Syncytial Virus Vaccines in Asthmatic Children", Pediatric Research, 8:689-696, 1974.
Mills et al., "Experimental Respiratory Syncytial Virus Infection of Adults", The Journal of Immunology, 107:123-130, 1971.
Murphy et al., "Enhanced pulmonary histopathology is observed in cotton rats immunized with formalin-inactivated respiratory syncytial virus (RSV) . . . ", Vaccine 8:497-502, 1990.
Norrby et al., "Site-directed serology with synthetic peptides representing the lage glycoprotein G of respiratory syncytial virus", Proc. Natl. Acad. Sci.

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