Monoclonal antidigoxtin antibodies

Details Monoclonal antidigoxtin antibodies Monoclonal antidigoxtin antibodies

1982-03-30

1989-02-07

Hazel, Blondel

Chemistry: molecular biology and microbiology

Spore forming or isolating process

424 858, 530387, 530388, 436548, C12N 500, G01N 3353, C07K 1502

Patent

active

048031674

ABSTRACT:
The present invention discloses a hybridoma culture and high affinity monoclonal antidigoxin antibodies produced by somatic cell fusion. The antibodies are useful for therapeutic as well as for diagnostic purposes. They are also useful in a model system for the study of structure-function relationships in antigen-antibody specific reactions.

REFERENCES:
Margolies, M. et al., Monoclonal Antibodies and T Cell Hybrd, pp. 367-374, Elseveer/North Holland Biomedical Press, Amsterdam, 1981.
Zurawski, Jr. et al., J. Immunology, vol. 121, No. 1, 1978.
Mudgett-Hunter et al., Abstracts of Fourth International Congress of Immunology, Paris, No. 19.2.14, 1980.
Novolny et al., FASEB Abstract, 40:1098, 1981.
Bany et al., Scand. J. Clin. Lab. Invest., vol. 41, pp. 75-78 (1981).
Mudgett-Hunter et al., Fed. Proc., vol. 39, No. 3, p. 928 (1980).
Sevier et al., Clin. Chem., vol. 27, No. 11, pp. 1797-1806 (1981).

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