Monoclonal antibody with specificity to human small cell carcino

Details Monoclonal antibody with specificity to human small cell carcino Monoclonal antibody with specificity to human small cell carcino

1983-12-14

1986-04-29

Wiseman, Thomas G.

Chemistry: analytical and immunological testing

Involving production or treatment of antibody

Monoclonal antibody

435 68, 4351721, 435240, 435259, 436 64, 436507, 436545, 436546, 436813, 436821, 260112B, 424 85, G01N 5300, G01N 3344, G01N 3353, G01N 3348, G01N 33564, C12N 1500, A61K 3900

Patent

active

045857423

ABSTRACT:
Monoclonal antibody reactive with SCC cells and unreactive with human neuroblastoma cells, human squamous cell carcinoma cells, and human large-cell undifferentiated lung carcinoma cells.

REFERENCES:
Baylin et al., Proc. Natl Acad. Sci., vol. 79, pp. 1650-1655, "A Unique Cell-Surface Protein Phenotype Distinguishes Human Small-Cell from Non-Small Cell Lung Cancer.
Mazauric et al., "Monoclonal Antibody-Defined Human Lung Living Cell Surface Protein Antigens", Cancer Research, V. 42, pp. 150-154, Jan. 1982.
Cuttitta et al., "Monoclonal Antibodies That Demonstrate Specificity For Several Types of Lung Cancer", Proc. Nat'l. Acad. Sci., V. 78, No. 7, Jul. 1981, pp. 4591-4595.

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