Monoclonal antibody which specifically binds to but does not...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...

Reexamination Certificate

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C435S346000, C530S388100

Reexamination Certificate

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10922682

ABSTRACT:
This invention provides a method of isolating CD8+cells which employs an antibody which specifically binds to CD8 molecules present on the surface of CD8+cells but does not activate the CD8+cells once bound. This invention also provides related hybridoma cell lines, monoclonal antibodies, antigenic polypeptides, isolated CD8+cells, and kits.

REFERENCES:
patent: 5593677 (1997-01-01), Reichert et al.
Colman et al., iResearch in Immunology (145(1):33-36, 1994.
Abaza et al., Journal of Protein Chemistry (11(5):433-444, 1992.
Lederman et al, Molecular Immunology (28:1171-1181, 1991.

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