Monoclonal antibody which neutralizes multiple strains of infect

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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43524027, 4351722, 530395, 530826, 530806, 530809, 424 858, C07K 1514, C07K 1528, C12N 1500, A61K 39395

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active

049564528

ABSTRACT:
Monoclonal antibodies effective in preventing infectious bursal disease in chickens, by neutralizing one or more virus strains thereof, have been isolated and obtained from deposited hybridomas. Vaccination of an entire poultry population with a vaccine prepared from these monoclonal antibodies gives a uniform level of protection against all strains of infectious bursal disease tested. The monoclonal antibodies were effective in inducing priming for an active anti-viral response in a heterologous host.

REFERENCES:
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patent: 4530831 (1985-07-01), Lutticken et al.
patent: 4559229 (1985-12-01), Page et al.
Azad et al., In Virology, 149, 190-198, (Mar. 1986).
Kohler et al., Nature, 256, 495-497, (1975).

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