Monoclonal antibody useful for the diagnosis of cancer

Details Monoclonal antibody useful for the diagnosis of cancer Monoclonal antibody useful for the diagnosis of cancer

1992-11-16

1994-06-14

Lacey, David L.

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

424 858, 43524027, 5303888, A61K 3500, A61K 3516, C07K 1528

Patent

active

053209567

ABSTRACT:
The invention provides novel monoclonal antibodies and the hybridomas that secrete them. The antibodies can be used for the diagnosis of a number of cancers, such as ovarian, esophageal and cervical carcinomas. A preferred antibody is secreted by a hybridoma deposited with the ATCC and has Accession No. HB 10570.

REFERENCES:
Waldmann Science 252:1657-1662 1991.
Blattler Cancer Cells 1(2):50-55 1989.
Riechmann et al. Nature 332:323-327 1988.
Abramowicz et al. New Eng J Med. Sep. 3, 1992 p. 736.
Blast et al. J Clin Invest 68: 1331-1337 '81.
Hamilton et al. Cancer Research 43:5379-5389 '83.

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