Monoclonal antibody to prostate secretory protein

Details Monoclonal antibody to prostate secretory protein Monoclonal antibody to prostate secretory protein

1986-10-20

1989-09-05

Nocker, Christine M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 68, 43524027, 436548, 436813, 935 99, 935100, 935101, 935102, 935103, 935104, 935110, 530387, G01N 33577

Patent

active

048638510

ABSTRACT:
Provided are hybridomas for producing monoclonal antibodies against human prostate secretory protein (PSP15), anti-PSP15 monoclonal antibodies, fragments and derivatives thereof, and methods for their use. The antibodies are monospecific, bind to protein A and are of the IgM class of immunoglobulins. The monoclonal antibodies are useful as basic diagnostics for detecting human prostate cancer cells.

REFERENCES:
patent: 4683200 (1987-07-01), Hirohashi et al.
patent: 4708930 (1987-11-01), Kortright et al.
patent: 4725538 (1988-02-01), Senger
Frankel et al., "Monoclonal Antibodies to a Human Prostate Antigen", Cancer Research, 42 (1982) pp. 3,714-3,718.
Starling et al., "Monoclonal Antibodies to Human Prostate and Bladder Tumor Associated Antigens", Cancer Research 42 (1982) pp. 3,084-3,089.
Loor, "Characterization and Utilization of Specific Monoclonal Antibodies to Serum Market Antigens of Prostate Cancer", Hybridoma 4 (1985 ) 77.

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