Monoclonal antibody to prostate-derived acid phosphatase and met

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 723, 5303882, 53038826, G01N 3353, C07K 1600, C12P 2108

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active

057190305

ABSTRACT:
According to the present invention, there are provided a monoclonal antibody to prostate-derived acid phosphatase and a method for determination of prostate-derived acid phosphatase using the monoclonal antibody. Prostate-derived acid phosphatase is boostered in animal and spleen cells isolated from the animal are fused with myeloma cells. The hybridoma capable of producing a monoclonal antibody having extremely high specificity to prostate-derived acid phosphatase is subjected to cloning. Using the monoclonal antibody produced by the hybridoma, prostate-derived acid phosphatase in a sample can be detected with extremely high sensitivity.

REFERENCES:
patent: 4474893 (1984-10-01), Reading
patent: 4690890 (1987-09-01), Loor et al.
Lee et al. Ann. NY Acad Sci, 1982, 390: 52-61.
Gericke et al, Clin. Chem. 28: 596-602, 1982.
Kuciel et al, Biotech Appl Biochem, 1988, 10: 257-272.
Hoyhtya, Acta Universitatis Ouluensis A 1988, 203: 1-71.
Guding, Journal of Immunological Methods 39, pp. 285-308 (1980).
Needham, Journal of Immunological Methods, 99, pp. 283-284 (1987).
Ferrante et al., Clin. exp. Immunol. 39, pp. 532-537, (1980).
Ferrante et al., Journal of Immunological Methods, 48, pp. 81-85 (1982).
Allen H. Minor et al., Blood, 7, pp. 693-699 (1952).
Tullis, Blood, 7, pp. 891-896 (1952).
Golub, Immunology, A Synthesis, pp. 98-101, Sinauer Associates, Inc. Sunderland, Massachusetts, 1987.
Suzuki et al., Molecular and Cellular Probes 2, pp. 157-167 (1988).
Suzuki et al., Clinical Chemistry, vol. 36, No. 1 pp. 153-156 (1990).
Gerber et al., Clin Chem. vol. 33, No. 7, pp. 1158-1162 (1987).
Landt et al., Clin Chem. vol. 34, No. 3, pp. 575-581 (1988).
Panteghini et al., Clinical Biochemistry, vol. 23 pp. 1-4 (1990).
Choe et al., Ann NY Acad Sci vol. 390, pp. 16-36 (1982).
Hoyhtya et al., Clin Chem vol. 33(1) pp. 103-107 (1987).
Lillehoj et al., Molecular Immunology, vol. 19, No. 9, pp. 1199-1202 (1982).
Yamaura et al., Journal of Immunological Methods vol. 84. pp. 105-116 (1985).

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