Monoclonal antibody to human ventricular myosin light chains

Details Monoclonal antibody to human ventricular myosin light chains Monoclonal antibody to human ventricular myosin light chains

1994-09-28

1997-12-30

Allen, Marianne P.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 792, 435 7021, 435331, 436518, 5303879, 5303881, G01N 3353

Patent

active

057029059

ABSTRACT:
A monoclonal antibody having high affinity to the cardiac isoform of human myosin light chains is described. The monoclonal antibody is prepared against a synthetic peptide from the amino terminal end of myosin light chain-1. The monoclonal antibody can be used as a reagent in an immunoassay system to identify blood, serum or plasma levels of myosin light chains. Such an immunoassay system can be used for diagnosing and quantifying myocardial necrosis and infarction.

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