Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1990-07-27
1992-12-01
Doll, John J.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
5303882, 5303884, C12N 512, C07K 1528
Patent
active
051680637
ABSTRACT:
A monoclonal antibody specific for enterohemorrhagic Escherichia coli 0157:H7 and 026:H11 is produced by immunizing BALB/c mice with a strain of E coli 0157:H7. The antibody reacts strongly by an enzyme-linked immunosorbent assay with a 13,000 dalton molecular weight outer membrane protein of strains of enterohemorrhagic Escherichia coli 0157:H7 and 026:H11.
REFERENCES:
Biological Abstracts, vol. 89, No. 5, Issued Mar. 1, 1990, V. V. Padhye et al., "Production and Characterization of Monoclonal Antibodies to Verotoxins 1 and 2 from Escherichia coli of Serotype 0157:H7", the abstract No. 48707, J. Med. Microbiol., 1989, 30(3), 219-226.
Gastroenterology, vol. 94, No. 9, Issued Mar. 1988, S. Tzipori et al., "Studies in Gnotobiotic Piglets on Non-0157:H7 Escherichia coli Serotypes Isolated from Patients with Hemorrhagic Colitis," pp. 590-597, see the abstract.
Journal of Clinical Microbiology, vol. 26, No. 10, Issued Oct. 1988, L. P. Perera et al., "Isolation and Characterization of Monoclonal Antibodies to Shiga-Like Toxin II of Enterohemorrhagic Escherichia coli and Use of the Monoclonal Antibodies in a Colony Enzyme-Linked Immunosorbent Assay", pp. 2127-2131, see the Abstract.
Riley, Lee W. et al., 1983, "Hemorrhagic Colitis Associated With A Rare Escherichia coli Serotype," The New England Journal of Medicine, vol. 308, No. 12, pp. 681-685.
Levine, M. M. 1987, "Escherichia coli that Cause Diarrhea: Enterotoxigenic, Enteropathogenic, Enteroinvasive, Entrohemorrhagic, and Enteroadherent," Journal of Infectious Diseases, vol. 155, pp. 377-389.
Levine, M. M. et al., 1987, "A DNA Probe to Identify Enterohemorrhagic Escherichia coli of 0157:H7 and Other Serotypes that Cause Hemmorhagic Colitis and Hemolytic Uremic Syndrome," Journal of Infectious Diseases, vol. 156, pp. 175-182.
Ryan, Caroline A. et al., 1986, "Escherichia coli 0157:H7 Diarrhea in a Nursing Home: Clinical, Epidemiological, and Pathological Findings," Journal of Infectious Diseases, vol. 154, No. 4, pp. 631-638.
Doyle, Michael P. and Jean L. Schoeni, 1987, "Isolation of Escherichia coli 0157:H7 from Retail Fresh Meats and Poultry," Applied and Environmental Microbiology, vol. 53, No. 10, pp. 2394-2396.
Todd, E. C. D. et al., 1988, "Rapid Hydrophobic Membrane Filter-Enzyme Labeled Antibody Procedure for Identification and Enumeration of Escherichia coli 0157:H7 in Foods" Applied and Environmental Microbiology, vol. 54, pp. 2536-2540.
Samadpour, M. et al., 1990, "Evaluation of DNA probes for detection of Shiga-Like-Toxin Producing Escherichia coli in Food and Calf Fecal Samples," Appl. and Envir. Microb., vol. 56, pp. 1212-1215.
Pollard, D. R. et al., 1990, "Rapid and Specific Detection of Verotoxin Genes in Escherichia coli by the Polymerase Chain Reaction," J. Clin. Microb., vol. 28, pp. 540-545.
Padhye, V. V. et al., 1989, "Production and Characterization of Monoclonal Antibodies to Verotoxins 1 and 2 from Escherichia coli of Serotype 0157:H7," J. Med. Microb., vol. 30, pp. 219-226.
Bopp, C. A. et al., 1987, "Unusual Verotoxin-Producing Escherichia coli Associated with Hemorrhagic Colitis," J. Clin. Microbiol., vol. 25, pp. 1486-1489.
Karmali, M. A. et al., 1983, "Sporadic Cases of Hemolytic Uremic Syndrome Associated with Fecal Cytoxin and Cytoxin Producing Escherichia coli in Stools," Lancet, vol. i, pp. 619-620.
Perry, M. B. et al., 1988, "Identification of Escherichia coli Serotype 0157 Strains by Using a Monoclonal Antibody," J. Clin. Microbiol., vol. 26, pp. 1973-1978.
Smith et al., 1985, "Measurement of Protein Using Bicinchoninic Acid," Analytical Biochemistry, vol. 150, pp. 76-85 (determination of protein concentration).
Hancock, R. E. W. and H. Naikaido, 1987, "Outer Membranes of Gram-Negative Bacteria," Journal of Bacteriology, vol. 136, pp. 381-390 (isolating of outer membrane proteins).
Padhye, N. P. and M. P. Doyle, 1990, "Production and Characterization of Monoclonal Antibody to Escherichia coli" 0157:H7, Amer. Soc. for Microb. (Annual Mtg.) (Abstract) p. 14.
Doyle Michael P.
Padhye Nisha
Doll John J.
Futrovsky Susan L.
Wisconsin Alumni Research Foundation
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