Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1997-10-27
2000-06-20
Scheiner, Laurie
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303871, 5303877, 5303881, 5303888, 436 64, 4352872, C07K 1600
Patent
active
060779381
ABSTRACT:
Compositions of the instant invention comprise a monoclonal antibody designated as 21-9 which binds selectively with an 80 kDa matrix-degrading proteinase having an average molecular weight of about 80 kDa, which is active in the presence of Ca.sup.2, Mg.sup.2+ and Mn.sup.2+.
REFERENCES:
Lin et al., Characterization of a Novel, Membrane-bound, 80-kDa Matrix-degrading Protease from Human Breast Cancer Cells, J. Biol. Chem., 272(14): 9147-9152, (Apr. 14, 1997).
Dickson Robert B.
Lin Chen-Yong
Georgetown University
Scheiner Laurie
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