Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1987-03-23
1989-02-21
Hazel, Blondel
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
424 858, 43524027, 4351722, C07K 1504, H61K 39395, C12N 1500, C12N 500
Patent
active
048066290
ABSTRACT:
Hybrid cell line for production of monoclonal antibody to an antigen found on approximately 70% of normal human thymocytes. The hybrid is formed by fusing splenocytes from immunized CAF.sub.1 mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapuetic uses of the monoclonal antibody are also disclosed.
REFERENCES:
patent: 4172124 (1929-10-01), Koprowski
patent: 4196265 (1980-04-01), Koprowski
patent: 4284412 (1981-08-01), Hansen
McMichael et al., Eur. J. Immunol., vol. 9, pp. 205-210, 1979.
Janussy et al., J. Immunology, vol. 126, pp. 1608-1613, 1981.
Goldstein Gideon
Kung Patrick C.
Hazel Blondel
Ortho Pharmaceutical Corporation
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