Monoclonal antibody specific for human colon fibroblast-derived

Details Monoclonal antibody specific for human colon fibroblast-derived Monoclonal antibody specific for human colon fibroblast-derived

1986-08-13

1989-05-23

Nuckel, Christine M.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435 68, 4351722, 530387, C12N 1500, C07K 1500

Patent

active

048330850

ABSTRACT:
A monoclonal antibody is disclosed which is specific for human colon fibroblast-derived tissue plasminogen activator (t-PA), and which is useful for immunoaffinity chromatography purification of t-PA and determination of t-PA in a biological sample.

REFERENCES:
patent: 4568544 (1986-02-01), Hasegawa et al.
patent: 4751084 (1988-06-01), Feder et al.
Chemical Abstracts, vol. 105, Nos. 224438, 224439, Dec. 22, 1986
Pettersson et al., Haemostasis 11(Supp. 1), p. 75, Abst. 134 (1982).
Pettersson et al., Prog. Fibrinolysis 6, 191-194 (1983).
Nielsen et al., the EMBO J. 2(1), 115-119 (1983).
Matsuo et al., Thromb. Res. 36, 517-526 (1984).
MacGregor et al., Thromb. Haemos. 53(1), 45-50 (1985).
Schleef et al., Ibid. 53(1), 170-175 (1985).
Angles-Cano et al., Blood 66(4), 913-920 (1985).
Holvoet et al., Ibid, 67(5), 1482-1487 (1986).
Einarrson et al., Biochim. Biophys. Acta 830, 1-10 (1985).
Reagan et al., Thromb. Res. 40, 1-9 (1985).
Tissot and Bachman, Prog. Fibrinolysis 6, 133-135 (1983).

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