Monoclonal antibody specific for activated lymphocytes and monoc

Details Monoclonal antibody specific for activated lymphocytes and monoc Monoclonal antibody specific for activated lymphocytes and monoc

1992-09-08

1997-07-01

Saunders, David

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 724, 53038824, 53038873, 53038875, 5303888, 53038885, C07K 1622, C07K 1630

Patent

active

056437404

ABSTRACT:
Hybrid cell line producing monoclonal antibodies reactive with human activated lymphocytes, monocytes and cancer cells directed against a growth factor of approximately 15,000 daltons. Diagnostic and therapeutic uses of the antibody and antigen in cancer, autoimmune disease and transplant rejection are discussed.

REFERENCES:
patent: 5045451 (1991-09-01), Uhr et al.
J. Schlom, In S. Broder (ED.), Molecular and Cellular Research for Future Diagnosis and therapy, Williams and Wilkins, Baltimore, 1990. pp. 95-134.
R.J. Billing et al, Hybridoma, 1, 303-311, 1982.
S. Chatterjee et al, Hybridoma, 1, 369-377, 1982.
H. Takahashi et al, Lancet, 1155-1157, 19 Nov. 1983.

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