Monoclonal antibody recognizing membrane phospholipase A.sub.2 a

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 723, 435 794, 435 7021, 43524027, 436 64, 436540, 436548, 53038826, 5303913, G01N 33573, G01N 33541, C07K 1528, C12N 516

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053588495

ABSTRACT:
The present invention first provides monoclonal antibodies recognizing membrane phospholipase A.sub.2, namely, monoclonal antibodies PL-49, PL-71, PL-76, and PL-78, hybridomas producing them, methods for producing them, and immunoassays of membrane phospholipase A.sub.2 using them.
The immunoassay of PLA.sub.2 M is useful for the diagnosis of articular rheumatism, cancers, and a wide variety of inflammatory states.

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