Monoclonal antibody reacting specifically reacting with Fas...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S070210, C435S810000, C530S388150, C530S388200, C530S391700, C530S391300

Reexamination Certificate

active

06946255

ABSTRACT:
The invention provides monoclonal antibodies, which specifically react with a Fas ligand, or active fragments thereof, a production process of the monoclonal antibodies, which specifically react with a Fas ligand, hybridomas separately producing a monoclonal antibody, which specifically reacts with a Fas ligand present on a cell surface, a method of detecting a Fas ligand in a solution, and a kit for use in detecting a Fas ligand, comprising plurality of monoclonal antibodies against Fas ligand in combination.

REFERENCES:
patent: 4950588 (1990-08-01), Dattagupta et al.
patent: WO95/18819 (1995-07-01), None
patent: WO 95/27735 (1995-10-01), None
Stryer et al, in Biochemistry, Third edition, W H Freeman Company, New York, pp. 31-33, 1998.
Kuby et al., 1994, Immunology, second edition, pp. 85-96.
Abaza et al, J of Protein Chemistry 11(5): 433-444, 1992.
Ngo et al., 1994, The Protein Folding Problem and Tertiary Structure Prediction, pp. 492-495.
Harlow et al, in Antibodies a Laboratory Manual, 1988, Cold Spring harbor laboratory publication, Cold Spring Harbor, NY, pag chapter 6, pp. 155-149, 296-297, 340-341 and 626-629.
Campbell et al (in Monoclonal Antibody Technology, 1984, Elsevier Science Publisher, New York, NY, p. 1-32.
Suda et al, Cell 75: 1169-78, Dec. 1993.
Takahashi et al, International Immunology 6(10): 1567-74, Jun. 1994.
Harlow, E. and Lane, D, Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, pp. 555-612, 1988.
Goding, JW, Monoclonal Antibodies: Principles and Practice. Academic Press, New York, pp. 5-58, 1986.
Smith, JA, Current Protocols in Molecular Biology, Ausubel, et al., eds., Green Pub. Assn & Wiley Intersciences, pp. 11.0.1-11.16.13, 1992.
“Expression of the functional soluble form of human Fas ligand in activated lymphocytes”, Tanaka et al., The EMBO Journal, vol. 14, No. 6, pp. 1129-1135, Mar. 15, 1995.
“The Fas Death Factor”, Nagata et al., Science, vol. 267, No. 5203, pp. 1449-1456, Mar. 10, 1995.
“Role of Fas Ligand in Apoptosis Induced by Hepatitis C Virus Infection”, Mita et al., Biochemical and Biophysical Research Communication, vol. 204, No. 2, pp. 468-474, Oct. 28, 1994.
“Continuous cultures of fused cells secreting antibody of predefined specificity”, Köhler, et al. Nature, vol. 256, pp. 495-497, Aug. 7, 1995.
“Metalloproteinase-mediated Release of Human Fas Ligand”, Kayagaki et al., J. Exp. Med., vol. 182, pp. 1777-1783, Dec. 1995.
Takashi Suda et al.The Structure and the Function of the Fas Ligand, Abstract of Cell Technology,13(8), 738-744 (1994).
Takahashi, T. et al. “Human Fas ligand: gene structure, chromosomal location and species specificity”, International Immunology (1994) vol. 6, No. 10, P. 1567-1574.
Takahashi, T. et al. “Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand”, Cell (1994) vol. 76, P. 969-976.
Suda, T. et al. “Purification and characterization of the Fas-ligand that induces apoptosis”, J. Exp. Med. (1994) vol. 179, No. 3, p. 873-879.
Nobuyuki Kobayashi, et al.,Anti-Fas Monoclonal Antibody is Cytocidal to Human Immunodeficiency Virus-Infected Cells Without Augmenting Viral Replication,vol. 87. pp. 9620-9624 Dec. 1990.
Jun Ogasawara et al.Lethal Effect of the Anti-Fas Antibody in Micevol. 364 Aug. 26, 1993.
Naoki Hiramatsu et al.Immunohistochemical Detection of Fas Antigen in Liver Tissue of Patients With Chronic Heptatitis C,vol. 19, 1994 1354-1359.
Shino Hanabuchi et al.Fas and its Ligand in a General Mechanism of T-Cell Mediated Cytotoxicity,vol. 91, pp. 4930-4934, May 1994.
Rie Watanabe-Fukunaga et al.Lymphoproliferation Disorder in Mice Explained by Defects in Fas Antigen That Mediates Apoptosis.
Naoto Itoh et al.The Polypeptide Encoded by the CDNA for Human Cell Surface Antigen Fas can Mediate Apoptosis, Cellvol. 66, 233-234, Jul. 26, 1991.
Takashi Suda et al.Molecular Cloning and Expression of the Fas Ligand, a Novel Member of the Tumor Necrosis Factor Family,vol. 75-1169-1178, Dec. 17, 1993, Cell.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Monoclonal antibody reacting specifically reacting with Fas... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Monoclonal antibody reacting specifically reacting with Fas..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monoclonal antibody reacting specifically reacting with Fas... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3439053

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.