Monoclonal antibody, polypeptides and production thereof

Details Monoclonal antibody, polypeptides and production thereof Monoclonal antibody, polypeptides and production thereof

1994-06-06

1995-08-08

Furman, Keith C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

435 72, 435 721, 435 723, 4352402, 43524023, 514 2, 530350, 536 221, 536 231, 536 235, A61K 3900, C07K 200, C07K 400, C07H 1900

Patent

active

054398860

ABSTRACT:
The present invention relates to a monclonal antibody capable of suppressing the motility of cancer cells, a polypeptide recognizable by said anti-cancer antibody and its fragment peptides which is capable of suppressing the motility of cancer cells.
The present invention also relates to a production and a use for preventing the matastasis of cancer thereof.

REFERENCES:
Yamada, et al. Cancer Research, 50(15):4485-4496 (1990).
Lanza, et al. Journal of Biological Chemistry, 266(16):10638-10645 (1991).
Miyake, et al., Journal of Experimental Medicine, 174(6:1347-1354 (1991).
Perlstein et al., "Effects of Antiplatelet antibody . . . ", Cancer Research 44, 3884-3887 Sep. 1984.
M. Miyake et al., "A Specific Cel Surface Glcoconjugate Controlling Cell Motility" Biochemistry, 30, (1991), pp. 3328-3334.
C. Boucheix et al., "Molecular Cloning of the CD9 Antigen" J. Biol. Chem. (1991) pp. 117-122.

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