Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1988-07-20
1990-08-28
Draper, Garnette
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530390, 530391, 530388, 530808, 424 859, 424 8591, 514885, C07K 1512, A61K 3900
Patent
active
049526766
ABSTRACT:
A platinum co-ordination compound linkable to a monoclonal antibody by a functional group which forms part of a moiety which stabilizes the antibody against in vivo hydrolysis. Also the use of such compounds in the treatment of cancer.
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Monoclonal Antibodies and Cancer Therapy, ed., Reisfeld et al., 1985, pp. 245-246 and 251-252.
Organometallic and Coordination Chemistry of Platinum, 1974, ed., Academic Press, Belluco.
Cleare Michael J.
Heffernan James G.
Picker Donald H.
Draper Garnette
Johnson Matthey PLC
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