Monoclonal antibody NUH2 capable of inactivating motility of hum

Details Monoclonal antibody NUH2 capable of inactivating motility of hum Monoclonal antibody NUH2 capable of inactivating motility of hum

1988-07-15

1993-07-13

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Lymphokine

424 88, 437 7, 437 89, 5303875, 5303882, 514843, A61K 3900, A61K 3514, H01L 4900, H01L 2120

Patent

active

052271609

ABSTRACT:
Monoclonal antibody NUH2 produced by a hybridoma having ATCC deposit no. HB 9762. An isolated antigen capable of specifically binding to anti-human sperm antibodies including NUH2 and comprising at least an epitope having a sialyl I structure, and any analogues derived from said antigen. Methods of using the monoclonal antibody and antigen for contraception and treating infertility in human females.

REFERENCES:
patent: 4795634 (1989-01-01), Grimes et al.
patent: 5051251 (1991-09-01), Morita et al.
patent: 5051425 (1991-09-01), Nakai
patent: 5051445 (1991-09-01), Louis et al.
Pharmaceutical Technology, Parrott, Burgess Publ. Co., MN, 1970.
Selected Methods in Cellular Immunology, Mishell & Shiigi, W. H. Freeman, S. F., 1980.
Essential Immunology, Roitt, Blackwell, Oxford, 1971.

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