Monoclonal antibody NKY13

Details Monoclonal antibody NKY13 Monoclonal antibody NKY13

1988-05-26

1991-12-17

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

530327, 435 7021, 4351722, C12N 520, C12N 1502, C07K 1528, C12P 2108

Patent

active

050734938

ABSTRACT:
Monoclonal antibody NKY13 recognizing sugar chains of mucin-type glycoproteins secreted by cancer cells, for example, the following sugar chains, and hydridoma producing it: ##STR1## The monoclonal antibody NKY13 renders it possible to make highly sensitive judgements in the serodiagnosis of such cancers as colon cancer, stomach cancer and pancreas cancer.

REFERENCES:
Schlorn et al., Cancer Res. 46:3225-28 1986.
Magnani et al., J. Biol. Chem. 257(22):14365-9, 1982.
Fukushi et al., Biochemistry 25:2859-66, 1986.
Wieruszeski et al., Carbohydrate Res. 137:127-38, 1985.
Mansson et al., Biochimica et Biophysicci Acta 834: 110-117, 1985.
Kipps et al., pp. 108.1-108.9 in Weir et al., Eds. "Handbook of Expt'l. Immunology", vol. 4, Blackwell Sci. Publ., 1986.
Brockhaus et al., Vox Sang. 48:34-38, 1985.

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