Chemistry: analytical and immunological testing – Thyroid hormone tests
Patent
1982-05-21
1985-04-30
Padgett, Benjamin R.
Chemistry: analytical and immunological testing
Thyroid hormone tests
436510, 436518, 436536, 436542, 436548, 436804, 436817, 436818, 435 7, 935110, G01N 3354, G01N 3374, G01N 3376
Patent
active
045145059
ABSTRACT:
Mixtures of monoclonal antibodies which contain effective assaying amounts of each of at least two monoclonal antibodies that bind to different antigenic sites on the antigen and are capable under appropriate conditions of binding simultaneously to an antigen are useful in enhanced sensitivity assays for the antigen. By utilizing such mixtures in diagnostic assays for important antigens such as the polypeptide human chorionic gonadotropin enhanced sensitivity can be achieved as compared with assays employing individual monoclonal antibodies.
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Canfield Robert E.
Ehrlich Paul H.
Moyle William R.
Moskowitz M.
Padgett Benjamin R.
The Trustees of Columbia University in the City of New York
White John P.
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