Monoclonal antibody in destruction of small cell lung carcinoma

Details Monoclonal antibody in destruction of small cell lung carcinoma Monoclonal antibody in destruction of small cell lung carcinoma

1995-01-24

1996-06-04

Feisee, Lila

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Binds specifically-identified oligosaccharide structure

4241331, 4241741, 4241811, 4241551, 5303888, 53038885, 5303873, A61K 39395, C07K 1618, C07K 1630

Patent

active

055230857

ABSTRACT:
Monoclonal antibody BR55-2 and fragments thereof having the specificity of monoclonal antibody BR55-2, and variants thereof, are useful in the treatment of small cell lung carcinoma.

REFERENCES:
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Laemmli, Nature, vol. 227, pp. 680-685 (1970).
Wilson et al, Immunofluorescence and Related Staining Techniques, Knapp et al--editors, pp. 215-224 (1978).
Colvin, Diagnotic Immunopathology, Raven Press, New York, pp. 437-452 (1988).
Steplewski, Z. et al., Hybridoma, vol. 9(2):201-210, 1990.
Scholz, D. et al., Cancer Immunol Immunother, 33:153-157, 1991.
Waldmann, T., Science, 252:1657-1662, 21 Jun. 1991.
Osband, M. E. et al., Immunology Today, 11(6):193-195, 1990.
Kannagi, R. et al, Handbook of Exp. Immunol, 4:117.1-117.20, May 30, 1986.

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