Monoclonal antibody formulation for diagnostic use

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435 7, 435 29, 436513, 436520, 436548, 436808, 436826, G01N 3353, G01N 33577, G01N 33555

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active

046184864

ABSTRACT:
Aqueous formulation containing monoclonal antibodies active against cell-bound antigens, particularly human red cell antigens, the said formulation containing a soluble salt in a concentration of not less than about 200 mmoles/1.

REFERENCES:
patent: 4164558 (1979-08-01), non Schulthess et al.
Moore, et al. (1976) Transfusion, vol. 16, No. 4 pp. 291-296.
Rock, et al. (1978) Transfusion, vol. 18, No. 2 pp. 228-232.
Jorgensen (1980) Vot Sanguinis, vol. 36, pp. 186-191.
Anstee, D. J.: Characterization of Human Blood Group Alloantigens. Monoclonal Antibodies in Clinical Medicine. (Ed. McMichael, A. J.; Fabre, J. W. Academic Press, London 1982). pp. 237-249.
Voak, D. et al., Monoclonal Anti-A from a Hybrid-Myeloma: Evaluation as a Blood Grouping Reagent. Vox Sang. 39: 134-140 (1980).
Sacks, S. H. et al., Monoclonal Anti-B as a New Blood-Typing Reagent. Vox Sang. 40: 99-104 (1981).
Edelman, L. et al., Thermodynamic and Immunological Properties of a Monoclonal Antibody to Human Blood Group A. Immunology 44: 549-554 (1981).
Bundle, D. R. et al., Hybridomas Specific for Carbohydrates; Synthetic Human Blood Group Antigens for the Production, Selection, and Characterization of Monoclonal Typing Reagents. J. Immunol. 129: 678-682 (1982).
Majdic, O. et al., Hybridomas Secreting Monoclonal Antibodies to Human Group A Erythrocytes. Immunobiology 156: 226-227 (1979).
Voak, D. et al., Monoclonal Anti-A and Anti-B: Development as Cost-Effective Reagents. Med. Lab. Sci. 39: 109-122 (1982).
Stahli, C. et al., High Frequencies of Antigen-Specific Hybridomas; Dependence on Immunization Parameters and Prediction by Spleen Cell Analysis. J. Immunol. Meth. 32; 297-304 (1980).
Dodge, J. T. et al., The Preparation and Chemical Characteristics of Hemoglobin-Free Ghosts of Human Erythrocytes. Arch. Biochem. Biophys. 100: 119-130 (1963).
Nowinski, R. C. et al., The Isolation of Hybrid Cell Lines Producing Monoclonal Antibodies Against the p. 15 (E) Protein of Ecotropic Murine Leukemia. Virology 93: 111-126 (1979).
Kennett, R. H., Monoclonal Antibodies (Ed. Kennett, R. H., McKearn, T. J.; Bechtol, K. B.) Plenum Press, New York 1980, pp. 365-367.
Fazekas de St. Groth, et al., Production of Monoclonal Antibodies: Strategy and Tactics. J. Immunol. Meth. 35: 1-21 (1980).
Engwall, E. et al., Enzyme-Linked Immunosorbent Assay, ELISA. III. Quantitation of Specific Antibodies by Enzymelabeled Anti-Immunoglobulin Antigen-Coated Tubes. J. Immunol. 109: 129-135 (1972).
Ouchterlony, O.: Diffusion-in-Gel Methods for Immunological Analysis I. Progr. Allergy 5: 1-78 (1958).
Messeter, L. et al. Automated Blood Grouping of Patients and Blood Donors Using Groupamatic 360 S and a Separate Minicomputer. Vox Sang. 33: 116-123 (1977).
Race, R. R. et al. Blood Groups in Man. 5th Ed. (Blackwell, Oxford 1968) p. 23.
European Agreement on the Exchanges of Blood-Grouping Reagents. European Treaty Series No. 39 (Council of Europe, Strasbourg, 1962).
Gooi, H. C. et al. Natural Antibodies as Contaminants of Hybridoma Products, Biochem. Biophys. Res. Comm. 106: 539-545 (1982).
Lennox, S.: Personal Communication, Hughes-Jones, N. C. et al. Optimal Conditions for Detecting Blood Group Antibodies by the Antiglobulin Test, Vox Sang. 9: 385-395 (1964).
Elliot, M. et al. Influence of Ionic Strength on the Serologic Behavior of Red Cell Isoantibodies, Vox Sang. 9: 396-414 (1964).
Moore, H. C. et al. The Effects of Ionic Strength on Antibody Uptake with Special Reference to the Antiglobulin Test, Ortho Second Internat. Symp. on "The Nature and Significance of Complement Activation", Raritan. N.J., 1979.

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