Monoclonal antibody capable of recognizing arteriosclerotic lesi

Details Monoclonal antibody capable of recognizing arteriosclerotic lesi Monoclonal antibody capable of recognizing arteriosclerotic lesi

1987-12-14

1992-05-05

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4351722, 436548, 530387, 530809, 935 95, 935103, 935106, C12N 1500, C12N 500, G01N 33577, C07K 1514

Patent

active

051107384

ABSTRACT:
The present invention is concerned with a monoclonal antibody capable of preferentially recognizing arteriosclerotic lesions and prepared from a hybridoma obtained by fusing myeloma cells and cells capable of producing antibodies against arteriosclerotic lesions, such as spleen cells, peripheral lymphocyte of thymus and peripheral vascular cells, the antibody can be to use as an agent for detecting the presence of arteriosclerotic lesions and for treating arteriosclerosis.

REFERENCES:
Roessner et al., Virchows Arch (Germany, West), vol. 412(2), pp. 169-174, 1987.
Glukhova et al., Tissue cell, vol. 19(5), pp. 657-663, 1987.
Tsukada et al., Arteriosclerosis, Nov.-Dec. 1986, vol. 6(6), pp. 601-613.
Gown et al., Am. J. Pathol., vol. 125(1), pp. 191-207, 1986 (Oct.).

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