Monoclonal antibody and use thereof

Details Monoclonal antibody and use thereof Monoclonal antibody and use thereof

2011-07-19

2011-07-19

Haddad, Maher M (Department: 1644)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Animal cell, per se, expressing immunoglobulin, antibody, or...

C424S133100, C424S139100, C530S388240, C530S388250, C435S007100

Reexamination Certificate

active

07981672

ABSTRACT:
The purpose of the invention is to provide an antibody which recognizes OPN N-half but does not recognize the full-length OPN, and its use. A monoclonal antibody which is characterized in that it recognizes a protein or polypeptide in which the C-terminal amino acid sequence is YGLR (SEQ ID NO: 1) and it substantially does not recognize a protein or polypeptide which has an amino acid sequence of YGLR outside of the C-terminal, as well as a method for measuring OPN N-half utilizing the said antibody, a method for diagnosing diseases relating to OPN N-half, a method for judging the severity of said disease, and a method for treating said diseases, are provided.

REFERENCES:
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