Monoclonal antibody against human platelets

Details Monoclonal antibody against human platelets Monoclonal antibody against human platelets

1992-01-07

1994-07-26

Lacey, David L.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

53038825, C12N 512, C07K 1528

Patent

active

053326709

ABSTRACT:
A novel anti-platelet monoclonal antibody which is without effect on inactivated platelets, but which augments platelet aggregation after minimal perturbation of the platelets, and various applications of the monoclonal antibody are described.

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Kelton, J. G., et al., Biological Abstracts, vol. 83(11), Abstract No. 108012, 1987.
Tuszynski, G. P., et al., Biological Abstracts, vol. 86(7), Abstract No. 66138, 1988.
Kambayashi, H., et al., "Leucocyte Typing III--White Cell Differentiation Antigens", edited by McMichael, A. J., et al, issued 1987 by Oxford University Press, p. 787.
Hsu-Lin et al, J. Bio. Chem. 259, 14, pp. 9121-9126 Jul. 1984.
Stenberg et al, J. Cell Bio. 101 pp. 880-886 Sep. 1985.
McEver, Blood Cells (1990) 16:73-83.

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