Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1993-11-03
1995-12-26
Parr, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
53038873, 5303893, 5303896, 530862, 435 71, 436513, 436536, 436540, 436548, 4241451, 4241531, 4241581, 4241721, C07K 1642, C07K 1618, G01N 3353, G01N 33577
Patent
active
054789265
ABSTRACT:
The present invention provides novel monoclonal antibodies HE-22A, HE-35A, HE-39E, and HE-69B against human IgE, a mixture thereof, hybridomas producing the antibodies, and immunoassays of human IgE employing the antibodies, which are useful for clinical diagnosis of allergic diseases or parasitic infections.
REFERENCES:
Nakamura et al., "Chapter 27" frm Handbook of Exp Immunol, vol. 1: Immunochemistry, Ed. D. M. Weir, Blackwell Sci Pub., 1986, pp. 27.1-27.20.
Anfosso et al, Conformational Differences of Human IgE on Hydrophobic and Hydrophilic Solid Phases Detected by Monoclonal Antibodies, Molec. Immunol., Nov. 1987, 24(11) pp. 1129-1134.
Chretien et al, A Monoclonal Anti-IgE Antibody Against an Epitope in the CH.sub.3 Domain Inhibits IgE Binding to the Low Affinity IgE Receptor, J. Immunol., Nov. 1988, 141(a) pp. 3128-3134.
Kornfeld et al, Interaction of Immunoglobulin Glycopeptides with Concanavalin A, J. Biol. Chem., Apr. 1975, 250(7), pp. 2614-2619.
Patent Abstracts of Japan, vol. 12, No. 398, p. 6 C 538 (1988).
Grassi et al, J. Allergy Clin. Immunol., vol. 77, No. 6, pp. 808-822 (1986).
Ichimori et al, Hybridoma, vol. 4, No. 1, pp. 47-53 (1985).
Harada Shigenori
Nishimura Shinji
Parr Margaret
Schwadron Ron
Shionogi & Co. Ltd.
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