Monoclonal antibody

Details Monoclonal antibody Monoclonal antibody

2005-02-01

2005-02-01

Kemmerer, Elizabeth (Department: 1647)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C530S387100, C530S388100, C530S391100, C530S391300

Reexamination Certificate

active

06849416

ABSTRACT:
A monoclonal antibody which is referred to as mAb 1E8, which was deposited at the DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH, Braunschweig, on Dec. 19, 2000 and which was assigned the DSMZ accession number DSM ACC2485, can be used for detecting Aβ peptides Aβ1-x and Aβ2-x, and sAPPα.

REFERENCES:
Chevallier, et al.; Cathepsin D Displays in Vitro Beta-Secretase-Like Specificity; 1997; pps. 11-19.
Takaomi Comings Saido, et al.; Spatial Resolution of the Primary Beta-Amyloidogenic Process Induced in Postischemic Hippocampus; The Journal of Biologial Chemistry; 1994; pps. 15253-15257.
Aria, et al: Immunohistochemical Localization of Amyloid Beta-Protein With Amino-Terminal Aspartate in the Cerebral Cortex of Patients with Alzheimer's Disease; Brain Research; 1999; pps. 202-206.
Wiltfang, et al.; Improved Electrophoretic Separation and Immunoblotting of Beta-Amyloid Peptides 1-40, 1-42, and 1-43; Electrophoresis; 1997; pps. 527-532.
Klafki, et al; Electrophoretic Separation of Beta-A4 Peptides; 1996; pps. 24-29.

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