Monoclonal antibodies which bind thromboxane A2 receptor antagon

Details Monoclonal antibodies which bind thromboxane A2 receptor antagon Monoclonal antibodies which bind thromboxane A2 receptor antagon

1989-11-17

1992-08-25

Doll, John

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

435 7021, 4351722, 435 792, 43524027, 435188, 436542, 424 858, C12N 520, C07K 1528

Patent

active

051418657

ABSTRACT:
Monoclonal antibodies which bind thromboxane A2 receptor antagonists, hybrid cell lines which produce these monoclonal antibodies, and immunoassay methods for detecting thromboxane A2 receptor antagonists using these monoclonal antibodies.

REFERENCES:
patent: 4663336 (1987-05-01), Nakane et al.
patent: 4975279 (1990-12-01), Schumacher et al.
G. Kohler et al., Nature 256, 495-497 (1975).
M. Reinke et al., FEBS Letters 232, 46-50 (1988).
Jaqoda et al., "A Specific Radioimmunoassay for the Measurement of a New Thromboxane Antogonist, SQ 30,741, in Plasma," Clin. Chem. 35(6): 1189, 1989.
Reinke et al., "A Monoclonal Anti-Thromboxane Bz Antibody," FEBS Letters 232(1):46-50, 1988.

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