Monoclonal antibodies to the Mystery Swine Disease virus

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 5, 435975, 43524027, 4241471, C07K 1610

Patent

active

056774290

ABSTRACT:
Monoclonal antibody sera can be produced by hybridoma technique. After immunization of a mouse, pig, rat, rabbit or other appropriate species with Mystery Swine Disease (MSD) containing cell culture lysate, the spleen of the animal can be removed and converted into a whole cell preparation. Preferably the monoclonal antibody is produced by a murine derived hybrid cell line wherein the antibody is an IgG or IgM type immunoglobulin. Example monoclonal antibodies to the infectious agent for SIRS are monoclonal antibody SDOW 12 and SDOW 17.

REFERENCES:
PHIND Database, PJB Publications Ltd., Surrey, GB: Abstract number 00278268 "Dutch team isolates mystery pig . . ." & Animal-Pharm 230, 21-06-01.
Database WPIL Week 8741, Derwent Publications Ltd., London. GB; AN 1987.
Database WPIL Week 8702, Derwent Publications Ltd., London. GB; AN Regional) 14 Jan. 1987.
Database WPIL Week 8821. Derwent Publications Ltd., London. GB; AN
R. Bilodeau et al., "`Porcine Reproductive and Respiratory Syndrome`in Quebec", The Veterinary Record, p. 102 (Aug. 3, 1991).
V. T. Christianson et al., "Swine Infertility and Respiratory Syndrome", Pig Vetrinary Journal, 27, 9 (Apr. 1991).
J. E. Collins et al., "Respiratory Disease in a Swine Herd Experiencing A Reproductive Failure Syndrome", Minnesota Swine Conference for Veterinarians, p. 254 (Sep. 16-18, 1990).
J. E. Collins et al., "Experimental Transmission of Swine Reproductive Failure Syndrome (Mystery Swine Disease) in Gnotobiotic Piglets", 71st Annual Meeting of the Conference of Research Workers in Animal Disease, Chicago, IL (Nov. 5 & 6, 1990), Abstract No. 2.
J. E. Collins et al., "Swine Infertility and Respiratory Syndrome (Mystery Swine Disease)", Minnesota Swine Confgerence for Veterinarians (Sep. 16, 1991).
K. K. Keffaber, "Reproductive Failure of Unknown Etiology", ASAP Newsletter, (Sep.-Oct. 1989).
K.K. Keffaber, "Swine Reproductive Failure of Unkown Etiology", The George A. Young Swine Conference & Annual Nebraska SPF Swine Conference, p. 55 (Aug. 13-14, 1990).
T. Loula, "Mystery Pig Disease", Agri-Practice, 12, 23 (Jan./Feb. 1991).
J. M. A. Pol et al., "Pathological Ultrastructural, and Immunohistochemical Changes Caused by Lelystad Virus in Experimentally Induced Infections of Mystery Swine Disease (Synonym: Porcine Epidemic Abortion and Respiratory Syndrome (PEARS)", The Veterinary Quaterly, 13, 137 (Jul. 1991).
C. Terpstra et al., "Experimental reproduction of Porcine Epidermic Abortion and Respiratory Syndrome (Mystery Swine Disease) by Infection with Lelystad Virus: Koch's Postulates Fulfilled", The Veterinary Quarterly, 13, 131 (Jul. 1991).
W. G. Van Alstine, "Mystery Swine Disease in the United States", Workshop/Seminar on the New Pig Disease In the European Community (Apr. 29-30, 1991).
G. Wensvoort et al., M. White, "`Blue Ear` Disease of Pigs", The Veterinary Record, 128, 574 (Jun. 15, 1991).
G. Wensvoort et al., "Mystery Swine Disease in the Netherlands; the Isolation of Lalystad Virus", The Veterinary Quarterly, 13, 121 (Jul. 1991).
K. H. Witte, "The Situation of `Epidermic Late Abortion of Swine` in the State of Northrhine-Westphalia", Workshop Seminar (Apr. 1991).
Animal Pharm., No. 228, p. 2 (May 24, 1991).
"Blue-Eared Disease Suspected in Two More Counties", The Veterinary Record, 129 (Jul. 6, 1991).
Proceedings of the Mystery Swine Disease Committee Meeting, Denver, CO (oct. 6, 1990).
D. A. Benfield et al., "Etiologic Agent of Swine Infertility and Respiratory Syndrome in the United States", 72st Annual Meeting of the Conference of Research Workers in Animal Disease, Chicago, Il (Nov. 11 & 12, 1991), p. 48, Abstract No. 268.
W. T. Christianson et al., "Experimental Reproduction of a Newly Described Viral disease, Swine Infertility and Respiratory Syndrome (SIRS), in Pregnant Sows", 72st Annual meeting of the Conference of Research Workers in Animal Disease, Chicago, IL (Nov. 11 & 12, 1991), p. 48, Abstract No. 269.
J. E. Collins, "Newly Recognized Respiratory Syndromes in North American Swine Herds", American Association of Swine Practioners Newsletter, 3, 7 (Sep.-Oct., 1991).
E. B. Morrison et al., "Sero-epidemiologic Investigation of Swine Infertility and Respiratory Syndrome (SIRS)", 72st Annual Meeting of the Conference of Research Workers in Animal Disease, Chicago, II (Nov. 11 & 12, 1991), p. 55, Abstract No. 309.
T. Quaife, "Mystery Agent Isolated", Swine Practioner, p. 4 (Nov. 1991).
F. W. von Busse, "Epidemiologic Studies on Porcine Reproductive and Respiratory Syndrome" (PRRS), Tier rrzzliche Umschau, p. 708 (Dec. 1991) (Abstract in English--p. 711).
V. F. von Ohlinger, "Aetiological Sutdies of the Porcine Reproductive and Respiratory Syndrome" (PRRS), Tier rzliche Umschau, p. 708 ( Dec. 1991) (Abstact in English--p. 703).
Porcine Reproductive and Respiratory Syndrome: A Report on the Seminar Held in Brussels on 4-5 Nov. 1991 and Organized by the European Commission.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Monoclonal antibodies to the Mystery Swine Disease virus does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Monoclonal antibodies to the Mystery Swine Disease virus, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monoclonal antibodies to the Mystery Swine Disease virus will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1556372

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.