Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2005-02-01
2005-02-01
Chin, Christopher L. (Department: 1641)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C424S143100, C435S005000, C435S007210, C435S070210, C435S452000, C435S332000, C435S334000, C436S518000, C436S548000, C436S820000, C530S413000
Reexamination Certificate
active
06849720
ABSTRACT:
There are provided monoclonal antibodies to the LDL receptor which are useful for the identification and purification of LDL and in treatment of e.g. hepatitis C infection.
REFERENCES:
patent: 5723438 (1998-03-01), Rubinstein et al.
van Driel et al., 1989. Stoichiometric binding of low density lipoprotein (LDL) and monoclonal antibodies to LDL receptors in a solid phase assay. J. Biol. Chem. 264(16): 9533-9538.*
Xie Chong-lun et al., 1991. Preparation and properties of monoclonal antibodies against low density lipoprotein (LDL) receptors. Acta Biochim. Biophys. Sinica 23(3): 189-195.*
Agnello et al., 1999. Hepatitis C virus and otehe Flaviviridae viruses enter cells via low density lipoprotein receptor. PNAS 96(22): 12766-12771.*
Caruso et al., 1993. Demonstration of low density lipoprotein receptor in human colonic carcinoma ans surrounding mucosa by immunoenzymatic assay. Ital. J. Gastroenterol. 25: 361-367.*
Owens et al., 1994. The genetic engineering of monoclonal antibodies. J. Immunolog. Meth. 168: 149-165.*
Hay et al., eds., 1992. American Type Culture Collection Catalogue of Cell Lines and Hybridomas. Seventh Edition, 1992. American Type Culture Collection, Rockville. p. 346.
Antonetti Francesco
Belzer Ilana
Dreano Michel
Smolarsky Moshe
Suissa Dany
Applied Research Systems ARS Holding N.V.
Browdy and Neimark
Chin Christopher L.
Grun James L.
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