Monoclonal antibodies to PDGF

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 794, 4351722, 43524027, 435948, 435975, 436548, 436808, 436824, 53038824, 5303913, 530413, 530809, 935104, 935108, 935110, C07K 1528, G12N 520, G01N 33577

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active

050949411

ABSTRACT:
Monoclonal antibodies (MAbs) capable of binding to native PDGF, and MAbs capable of specifically binding to the PDGF-AA, PDGF-BB and PDGF-AB isoforms are disclosed. The subject MAbs may be used in the detection or purification of native PDGF or selected PGDF isoforms. In addition, the MAbs may be labeled with an imaging agent and used for in vivo diagnostic purposes, or combined with a pharmaceutically acceptable carrier or diluent for use within wound healing compositions.

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