Monoclonal antibodies to mycosphaerella species

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 792, 435 794, 43524027, 435 7021, 5303885, 5303891, 5303911, 5303913, G01N 3353, G01N 33569, C07K 1600, C12P 2108

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active

055589979

ABSTRACT:
The invention relates to monoclonal antibodies that react specifically with members of the genus Mycosphaerella and hybridomas that produce such antibodies. The invention is further directed to a method for making a hybridoma cell line that produces monoclonal antibodies that react specifically with at least one species of Mycosphaerella, and a method of obtaining monoclonal antibodies therefrom. Methods and kits for diagnosing Mycosphaerella infections in plant material using such monoclonal antibodies are also within the scope of the invention.

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Farr et al., Fungi on Plants and Plant Products in the United States, APS Press, St. Paul, Minn: 799-807 (1989).
Fries et al., "Identity of the Fungal Endophyte of Ascophyllum with Mycosphaerella ascophylli Established by Means of Fluorescent Antibody Tehcnique", Botanica Marina, 21: 409-411 (1978).
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MacDonald et al., "Detection of Low-M.sub.r Glycoproteins in Surface Washes of Some Fungal Cultures by Gel-filtration HPLC and by Monoclonal Antibodies", J. Gen. Microbiol. 135: 375-383 (1989).
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