Monoclonal antibodies to melanoma cells

Details Monoclonal antibodies to melanoma cells Monoclonal antibodies to melanoma cells

1988-03-11

1991-04-23

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

530387, 530388, 43524027, 435 7021, 4351722, 424 858, 424 8591, 436548, G01N 33535, C07K 1528, C12N 518, A61K 3900

Patent

active

050099957

ABSTRACT:
This invention relates to monoclonal antibodies recognizing the gp130 antigen of human cells. Monoclonal antibodies which recognize distinct determinants on this antigen and methods of detecting the determinants by immunoassay with the monoclonal antibodies which recognize them are disclosed. The monoclonal antibodies are useful in the detection of the gp130 antigen and human cells including melanoma which contain this antigen.

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Dippold et al., British J. Cancer 43:561, 1981.
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Dippold et al., PNAS, U.S.A. 77:6114-8, Oct. 1980.
Lakin et al., J. Neurochem. 37: 1170-8, 1981.

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