Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1987-07-01
1988-10-25
Kepplinger, Esther M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
43524027, 4351722, 435810, 424 87, 424 88, 436548, 530387, 935103, 935107, 935110, G01N 33569, G01N 33577, C12N 500, A61K 3940
Patent
active
047804076
ABSTRACT:
A process to produce hybrid cell lines, which produce monoclonal antibodies to Legionella pneumophila. Cell lines are produced by fusion of immunized mouse splenocytes to these bacteria with non secreting myeloma cells.
Monoclonal antibodies are useful for diagnosis of diseases due to Legionella pneumophilia, for detection of these bacteria in environment, for the production of vaccines.
REFERENCES:
patent: 4376110 (1983-03-01), David et al.
Wong et al., Annals of Internal Medicine, 90: 634-638, 1979.
Kohler et al., Nature, vol. 256: 495-497, 1975.
Para et al., J. of Clinical Microbiology, 18: 895-900, 1983.
Biological Abstracts, vol. 73, 1982, No. 32777; C. R. Rinaldo, Jr. et al.: "Growth of the Pittsburgh Pneumonia Agent in Animal Cell Cultures", & Infect Immun 33(3): 939-943, 1981.
Guillet Jean G.
Hoebeke Johan
Strosberg Arthur D.
Tram Cuong
Centre National de la Recherche Scientifique
Institut Pasteur
Kepplinger Esther M.
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