Monoclonal antibodies to human pulmonary surfactant apoprotein D

Details Monoclonal antibodies to human pulmonary surfactant apoprotein D Monoclonal antibodies to human pulmonary surfactant apoprotein D

1995-03-07

1997-09-23

Spiegel, Carol A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 71, 435 4052, 436518, 436536, 436548, 436907, 5303882, 53038825, 53038885, 5303913, G01N 3353

Patent

active

056703287

ABSTRACT:
A monoclonal antibody which is capable of specifically binding with human pulmonary surfactant apoprotein D has been successfully obtained. Using the monoclonal antibody, human pulmonary surfactant apoprotein D can be specifically detected and assayed, whereby diagnosis of respiratory diseases is enabled.

REFERENCES:
patent: 4562003 (1985-12-01), Lewicki
patent: 5156950 (1992-10-01), Akino
Shimizu et al., "Primary Structure of Rat Pulmonary Surfactant Protein D", Journal of Biological Chemistry, vol. 267, No. 3, Jan. 25, 1992, pp. 1853-1857.
Persson et al., "Surfactant Protein D is a Divalent Cation-Dependent Carbohydrate-Binding Protein", vol. 265, No. 10, Apr. 5, 1990, pp. 5755-5760.
Archives of Biochemistry and Biophysics, "Human Surfactant Protein D: SP-D Contains a C-Type Lectin Carbohydrate Recognition Domain", Rust et al., vol. 290, No. 1, Oct., pp. 116-126 (1991).

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