Monoclonal antibodies to human pancreatic cancer

Details Monoclonal antibodies to human pancreatic cancer Monoclonal antibodies to human pancreatic cancer

1989-04-03

1990-10-09

Warden, Robert J.

Chemistry: analytical and immunological testing

Involving production or treatment of antibody

Monoclonal antibody

4351722, 43524027, 530387, 530808, 530809, G01N 3353, C12N 1500

Patent

active

049620487

ABSTRACT:
Novel hybridoma cell lines producing monoclonal antibodies which react specifically with human pancreatic cancer cells are described. Methods for producing antigenic preparations to generate the hybridoma cell lines and for selecting, purifying and characterizing the monoclonal antibodies reactive with human cells, including pancreatic cancer cells, are disclosed.

REFERENCES:
patent: 4444744 (1984-04-01), Goldenberg
patent: 4485093 (1984-11-01), Runge
patent: 4664911 (1987-05-01), Uhr et al.
Schmiegel et al., Cancer Research, vol. 45, pp. 1402-1407 (Mar. 1985).
Kohler et al., Nature, vol. 256, pp. 495-497 (Aug. 1975).
Akiyama et al., Chemical Abstracts, vol. 106:100759e (1987).

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