Monoclonal antibodies to human leukemia inhibitory factor

Details Monoclonal antibodies to human leukemia inhibitory factor Monoclonal antibodies to human leukemia inhibitory factor

1994-06-13

1997-11-18

Hutzell, Paula K.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

53038823, 435 71, C07K 1624, C12P 2108, C12N 520, G01N 3353

Patent

active

056886810

ABSTRACT:
The invention relates to monoclonal antibodies to human leukemia inhibitory factor. The disclosed monoclonal antibodies are believed to recognize unique epitopes on hLIF and are useful in the treatment of conditions wherein the presence of hLIF causes or contributes to undesirable pathological effects, such as cachexia, dysregulated calcium metabolism, or excessive bone cell proliferation, and in the detection of hLIF, for example, in clinical samples or specimens.

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