Monoclonal antibodies to human influx peptide transporter

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide

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435 696, 43524027, 5303871, 5303873, 5303882, 53038835, 4241521, C07K 1600, C12P 1208

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058245103

ABSTRACT:
Monoclonal antibodies which react with the human influx peptide transporter are provided. The human influx peptide transporter-reactive antibodies are useful in the purification of influx peptide transporter and in immunoassays to identify agents taken up into the cell by the human influx peptide transporter mechanism. The monoclonal antibodies are also useful for the detection and treatment of carcinomas derived from the gastrointestinal tract and pancreatic duct.

REFERENCES:
patent: 5183756 (1993-02-01), Schlom
Dantzig and Bergin, 1990, Biochimica et Biophysica Acta 1027:211-217.
Dantzig et al., 1992, Biochimica et Biophysica Acta 1112:167-173.
Kramer et al., 1990, Biochimica et Biophysica Acta 1030:41-49.
Kramer et al., 1990, Biochimica et Biophysica Acta 1030:50-59.
Ganapathy and Leibach, 1991, Current Opinion in Cell Biology 3:695-701.
Kramer et al., 1991, International Congress of Chemptherapy, Berlin, F.R.G. Abstract No. 1415.
Bird and Lloyd, 1990, Biochimica et Biophysica Acta 1024:267-270.
Skopicki, et al., 1991, Am. J. Physiol. 261:F670-F678.
Ganapathy, et al., 1981, J. Biol. Chem. 256:118-124.
Said, et al., 1988, Biochim. Biophys. Acta 941:232-240.
Kramer, et al., 1988, Biochim. Biophys. Acta 939:167-172.
Calonge, et al., 1990, Am. J. Physiol. 259:G775-G780.
Shimada and Hoshi, 1986, Jpn. J. Physiol. 36:451-465.
Matthews and Burston, 1984, Clinical Sci. 67:541-549.
Okano, et al., 1986, J. Biol. Chem. 261:14130-14134.
Nakashima, et al., 1984, Biochem. Pharm. 33:3345-3352.
Muranushi, et al., 1989, Pharm. Res. 6:308-312.
Friedman and Amidon, 1989, Pharm. Res. 6:1043-1047.
U.S. application No. 08/013,462, Dantzig et al. filed May 4, 1993.
Friedman and Amidon, 1990, J. Control. Rel. 13:141-146.
Tabas, et al., 1991, 31st Interscience Conference on Antimicrobial Agents and Chemotherapy Abstract No. 164.
Dantzig, et al., 1992, 32nd Interscience Conference on Antimicrobial Agents and Chemotherapy, Anaheim, CA, Abstract No. 1460.
Snyder, et al., 1992, 32nd Interscience Conference on Antimicrobial Agents and Chemotherapy Abstract No. 1461.
Hoshi, 1986, Ion Gradient-Coupled Transport, INSERM Symposium No. 26. Editors: F. Alvarado and C. van Os, Elsevier Science Publishers.
Ganapathy and Leibach, 1983, J. Biol. Chem. 258:14189-14192.
Inui, et al., 1992, J. Pharmacol. Exp. Thera. 260:482-486.
Sezaki and Kimura, 1983, Topics in Pharmaceutical Sciences 133-142.
Okano, et al., 1986, Biochem. Pharmacol. 35:1781-1786.
Bai, et al., 1991, Pharm. Res. 8:593-599.
Kramer, 1987, Biochim. Biophys. Acta 905:65-74.
Miyamoto, et al., 1991, J. Biological Chemistry 266(8):4742-4745.
Kramer, et al., 1988, Biochem. Pharmacol. 37:2427-2435.
Sugawara, M., et al., 1992, J. Pharm. Pharmacol. 44:968-972.
Kramer et al (Abstract) Journal of Chromotography Nov. 23, 1990, 521 (2) pp. 199-210.
Carson et al. Advances in Immunology 1986. vol. 38 p. 275.
Waldmann Science vol. 252 p. 1657 1991.
Harris Tibteun 1993 vol. 11, p. 42.

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