Monoclonal antibodies to HIV-1 and methods of using same

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

Reexamination Certificate

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C424S130100, C530S387300, C530S388800, C530S388100, C530S388150, C435S007100

Reexamination Certificate

active

07993647

ABSTRACT:
The present invention provides monoclonal antibodies to HIV-1 Vpr and hybridoma cell lines that produce the monoclonal antibodies to HIV-1 Vpr. Methods for use of such antibodies in the detection of HIV-1 infection are also provided.

REFERENCES:
patent: 5780220 (1998-07-01), Weiner et al.
patent: 0 403 333 (1990-12-01), None
patent: 0 403 333 (1990-12-01), None
patent: WO 03/089472 (2003-10-01), None
patent: WO 03/089472 (2003-10-01), None
Kashmiri S. et al. “SDR grafting—a new approach to antibody humanization”. Methods. May 2005;36(1):25-34.
Tamura M. et al “Structural correlates of an anticarcinoma antibody: identification of specificity-determining residues (SDRs) and development of a minimally immunogenic antibody variant by retention of SDRs only”. J Immunol. Feb. 1, 2000;164(3):1432-41.
Kashmiri S. “SDR grafting—a new approach to antibody humanization” Methods 36 (2005) 25-34.
Presta, LG “Engineering Antibodies for Therapy” Current Pharmaceutical Biotechnology, 2002, 3, 237-256 237.
Köhler G, Milstein C. “Continuous cultures of fused cells secreting antibody of predefined specificity. 1975” J Immunol. Mar. 1, 2005;174(5):2453-5. (Reprinted with permission from Nature 256 (5517): 495-497 (1975).
Levy, David, et al. “Serum Vpr regulates productive infection and latency of human immunodeficiency virus type 1,” Proc. Natl. Acad. Sci., 1994, vol. 91, pp. 10873-10877. XP-002345842.

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