Monoclonal antibodies to cyclodiene insecticides and method for

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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435 79, 436548, 436815, 5303889, C12N 520, C07K 1500

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active

053345282

ABSTRACT:
Methods are described for making specific monoclonal antibodies useful for detection of cyclodienes in foods and environmental samples. Monoclonal antibodies specifically reactive with cyclodienes can detect accumulated pesticides in food, tissue or environmental samples. Extraction and preparation of organic samples for immunoassay in a polar-nonpolar reaction medium permits detection of halogenated organic ring structures at concentrations in samples.

REFERENCES:
patent: 4056468 (1977-11-01), Breiter et al.
Vanderlaan, J., et al. "Monoclonal Antibodies for the Detection of Trace Chemicals: Pesticide Science and Biotechnology", Proceedings of the 6th International Congress of Pesticide Chemistry; Blackwell Scientific Publications, Oxford, England (1987) pp. 597-602.
Vanderlaan, M., et al. "Environmental Monitoring by Immunoassay" Environ. Sci. Technol., 22(3): 247-254 (1988).
Dreher, R. M. et al, "Development of an Enzyme Immunoassy for Endosulfan and Its Degradation Products" J. Agric. Food Chem. 36: 1072-1075 (1988).
Langone et al., Chem Abs 83:2009x. 1975.
Serier et al., Clin. Chem. 27(11), 1797-1806, 1981.

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