Monoclonal antibodies to cell surface antigens of human renal ca

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide

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435240, 435948, 4351722, 436548, C12P 2100, C12N 500, C12N 1500, C12R 191

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046507566

ABSTRACT:
The preparation and use of monoclonal antibodies to human renal tumor cells is described. The monoclonal antibodies bind to glycoproteins of 160Kd, 120Kd and 115Kd, a glycolipid, a HLA heavy chain, group A blood and group B blood antigens.

REFERENCES:
patent: 4172124 (1979-10-01), Koprowski et al.
Parham et al., "Use of a Monoclonal Antibody (W6/32) in Structural Studies of HLA-A,B,C Antigens" Journal of Immunology, vol. 123(1), (1979) pp. 342-349.
Voak, et al., "Monoclonal Anti-A from a Hybrid-Myeloma: Evaluation as a Blood Grouping Reagent", Vox Sanguinis, vol. 39, (1980) pp. 134-140.
Sacks et al., "Monoclonal Anti-B as a New Blood-Typing Reagent", Vox Sanguinis, vol. 40 (2-1981), pp. 99-104.
Ueda et al., "Cell Surface Antigens of Human Renal Cancer Defined by Autologous Typing", Journal of Experimental Medicine, vol. 150, (1979), pp. 564-579.
Dippold et al., "Cell Surface Antigens of Human Malignant Melanoma: Definition of Six Antigenic Systems with Mouse Monoclonal", Proceedings of the National Academy of Sciences, 77(10), (1980), pp. 6114-6118.
Houghton et al., "Serological Survey of Normal Humans for the Natural Antibody to Cell Surface Antigens of Melanoma", Proceedings of the National Academy of Sciences, 77(7), (1980), pp. 4260-4264.
Dippold et al., "p53 Transformation-Related Protein: Detection by Monoclonal Antibody in Mouse and Human Cells", Proceedings of the National Academy of Sciences, 78(3), (3-1981), pp. 1695-1699.
Catalogue of Cell Lines and Hybridomas--1985 ATCC, p. XV.

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