Monoclonal antibodies that bind to soluble IGE but do not bind I

Details Monoclonal antibodies that bind to soluble IGE but do not bind I Monoclonal antibodies that bind to soluble IGE but do not bind I

1989-03-06

1995-09-12

Hutzell, Paula K.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

53038825, 5303893, 43524027, C07K 1642, C12N 570

Patent

active

054497604

ABSTRACT:
Antibodies that bind soluble IgE but not IgE on the surface of B lymphocytes or basophils are described. The antibodies do not induce histamine release by basophils or mast cells.

REFERENCES:
Goding, "Monoclonal Antibodies: Principles and Practice" Academic Press, 1983, pp. 118-123.
Waldmann, Science 252: 1657-1667, 1991.
Morrison, Science 229: 1202-1207, 1985.
Hook et al. Fed Proc. 46:1346, 1987.

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