Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-03-25
1999-09-21
Loring, Susan A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 7021, 4351721, 4351722, 5303873, 536 2353, C12P 2106, C12P 2104, C12P 2108, C12N 1500
Patent
active
059553111
ABSTRACT:
Monoclonal antibodies that specifically bind to an extracellular domain of a VEGF receptor and neutralize activation of the receptor are provided. In vitro and in vivo methods of using these antibodies are also provided.
REFERENCES:
patent: 5270458 (1993-12-01), Lemischka
Folkman, J. and M. Klagsbrun, Science 235, 442-447 (Jan. 23, 1987).
Kapainen et al, J. Exp. Med. 178, 2077-2088 (Dec. 1993).
Kim et al., Nature 362, 841-844 (Apr. 29, 1993).
Matthews et al., PNAS USA 88, 9026-9030 (Oct. 1991).
Millaur et al., Cell 72, 835-846 (1993).
Plate et al., Cancer Research 53, 5822-5827 (Dec. 1, 1993).
Shibuya et al., Oncogene 5, 519-524 (1990).
Terman et al., Oncogene 6, 1677-1683 (1991).
Plate, et al., Nature 359, 845-848 (Oct. 1982).
Leung et al., Science 246, 1306-1309.
Rockwell et al., Molecular and Cellular Differentiation 3, 91-109 (1995).
Rockwell et al., Molecular and Cellular Differentiation 3, 315-335 (1995).
Goldstein Neil I.
Rockwell Patricia
ImClone Systems Incorporated
Loring Susan A.
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