Monoclonal antibodies specific for free N-acetylfuraminic acid a

Details Monoclonal antibodies specific for free N-acetylfuraminic acid a Monoclonal antibodies specific for free N-acetylfuraminic acid a

1988-11-08

1992-10-27

Doll, John J.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

5303889, 4351722, 435 7021, C12N 4520, C12N 520, C07K 1528, C12P 2108

Patent

active

051588862

ABSTRACT:
A hybridoma producing a monoclonal antibody specific for free N-acetylneuraminic acid or beta glycoconjugates thereof, is herein disclosed. The hybridoma can be generated by fusing (i) B cells of lymphocytes obtained by immunizing an animal with an N-acetylneuraminic acid or a beta-glycoconjugate thereof, and (ii) myeloma cells.

REFERENCES:
patent: 4694076 (1987-09-01), Ogawa et al.
The Journal of Biological Chemistry, vol. 262, No. 3, pp. 1358-1362, (1987), Katsuyoshi Shigeta et al.
Chapter 17 of Publication "Handbook of Experimental Immunology", vol. 4, pp. 117.1-117.20, (1986), Weir & Herzenberg.
Zeitschrift Fur Parasitenkunde, vol. 71, No. 5, 1985, pp. 663-672, Springer-Verlag, Berlin, DE; A. Bohn et al.: "Characterization of Antigens of the Nematode Nippostronylus Brasiliensis by Monoclonal Antibodies"*Abstract; p. 664, line 17-p. 665, line 22; p. 669, lines 7-12.
Proceedings of the National Academy of Sciences, vol. 76, No. 10, Oct. 1979, pp. 4913-4917, Washington, U.S.; G. S. Eisenbarth et al.; "Monoclonal Antibody to a Plasma Membrane Antigen of Neurons" * Abstract; pp. 4917, col. 1, lines 11-14.

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