Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-03-27
2007-03-27
Ceperley, Mary E. (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007940, C435S007950, C436S527000, C436S531000, C436S545000, C436S546000, C530S388900, C530S403000, C530S404000, C530S405000, C530S406000, C546S046000
Reexamination Certificate
active
10453256
ABSTRACT:
The present invention relates to monoclonal antibodies that specifically bind buprenorphine and/or at least one metabolic product thereof. The present invention further relates to buprenorphine metabolite conjugates for the production of monoclonal antibodies that specifically bind buprenorphine and/or at least one metabolic product thereof and hybridoma cells that produce the monoclonal antibodies. The invention also relates to immunoassay methods for determining buprenorphine and/or one or more buprenorphine metabolites in a sample using the novel antibodies and conjugates of the present invention.
REFERENCES:
patent: 4833073 (1989-05-01), McNally et al.
patent: 5292899 (1994-03-01), Tius et al.
patent: 5908927 (1999-06-01), Nguyen et al.
patent: 2004/036227 (2004-04-01), None
V. Cirimele et al, J. Analytical Toxicology, vol. 27, pp. 103-105 (2003).
Pope, L. et al., “Specific buprenorphine assay using CEDIA® technology,” Clinical Chemistry, vol. 49, No. 6, Supplement, Jul. 24, 2003, E-19.
Barlett, A. J. et al., “The Radioimmunoassay of Buprenorphine,” Eur. J. Clin. Pharmacol., 18, 339-345 (1980).
Debrabandere, L. et al., “Development of a Radioimmunoassay for the Determination of Buprenorphine in Biological Samples,” Analyst, Feb. 1993, vol. 118, pp. 137-143.
Hackett, L. P. et al., Journal of Chromatography, 374 (1986) 400-404.
Hand, C. W. et al., “Radioimmunoassay of buprenorphine with iodine label: analysis of buprenorphine and metabolites in human,”Ann. Clin. Biochem., 23: 47-53. (1986).
Hand, C. W. et al., “Radioimmunoassay of Buprenorphine in Urine: Studies in Patients and in a Drug Clinic,” Journal of Analytic Toxicology, vol. 13, Mar./Apr. 1989, pp. 100-104.
Moody, D. et al., “Determination of Buprenorphine in Human Plasma by Gas Chromatography-Positive Ion Chemical Ionization Mass Spectrometry and Liquid Chromatography-Tandem Mass Spectrometry,” Journal of Analytical Toxicology, vol. 21, Oct. 1997.
Ghoshal Mitali
Root Richard T.
Amick Marilyn L.
Ceperley Mary E.
Roche Diagnostics Operations Inc.
Roche Diagnostics Operations Inc.
LandOfFree
Monoclonal antibodies specific for buprenorphine and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Monoclonal antibodies specific for buprenorphine and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monoclonal antibodies specific for buprenorphine and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3789231